Transition Metal‐Catalyzed Regiodivergent C−H Arylations of Aryl‐Substituted Azoles

Ch-ch-ch-ch-Changes

Change is not made without inconvenience, even from worse to better. Richard Hooker, as quoted in the preface of Samuel Johnson's A Dictionary of the English Language Oh, so they have internet on computers now! Homer Simpson It is with great pleasure that I announce the rebirth of the former print journal of the Canadian Geriatrics Society as a new online publication, the Canadian Geriatrics Jo...

Enantioselective synthesis of gem-diarylalkanes by transition metal-catalyzed asymmetric arylations (TMCAAr)

Chiral gem(1,1)-diaryl containing tertiary or quaternary stereogenic centers are present in many natural products and important pharmacophores. While numerous catalytic asymmetric methods enable access to 1,1-diaryl motifs, transition metal-catalyzed asymmetric arylations (TMCAAr) are one of the most powerful methods to prepare enantiopure gem-diarylalkane compounds. The main methodology includ...

High resolution spectroscopy of Ar - CH 4 and Kr - CH in the 7 ( i region ( j = 1 < — 0 transition

für Naturforschung in cooperation with the Max Planck Society for the Advancement of Science under a Creative Commons Attribution 4.0 International License. Dieses Werk wurde im Jahr 2013 vom Verlag Zeitschrift für Naturforschung in Zusammenarbeit mit der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. digitalisiert und unter folgender Lizenz veröffentlicht: Creative Commons Namen...

Pharmacokinetic Drug Interactions of Azoles

Reactivity of bromoselenophenes in palladium-catalyzed direct arylations

The reactivity of 2-bromo- and 2,5-dibromoselenophenes in Pd-catalyzed direct heteroarylation was investigated. From 2-bromoselenophene, only the most reactive heteroarenes could be employed to prepare 2-heteroarylated selenophenes; whereas, 2,5-dibromoselenophene generally gave 2,5-di(heteroarylated) selenophenes in high yields using both thiazole and thiophene derivatives. Moreover, sequentia...